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Symbol Name ID |
Smad5
SMAD family member 5 MGI:1328787 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Mouse Phenotypes | cardiovascular system phenotype |
abnormal blood vessel morphology |
abnormal dorsal aorta morphology |
dilated dorsal aorta |
abnormal vascular endothelial cell morphology |
abnormal vascular development |
decreased angiogenesis |
abnormal vasculogenesis |
abnormal vitelline vasculature morphology |
absent vitelline blood vessels |
disorganized yolk sac vascular plexus |
vascular smooth muscle hypotrophy |
abnormal heart development |
failure of heart looping |
abnormal heart tube morphology |
delayed heart development |
dilated heart |
hemorrhage |
decreased cardiac muscle contractility |
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| Availability | Mouse Genotype | |||||||||||||||||||
| Smad5tm1.1Huy/Smad5tm1.1Huy | ||||||||||||||||||||
| Smad5tm1Cxd/Smad5tm1Cxd | ||||||||||||||||||||
| Smad5tm1Zuk/Smad5tm1Zuk | ||||||||||||||||||||
| Smad5tm1Huy/Smad5tm1.1Huy Tg(Tagln-cre)1Her/0 (conditional) |
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| Smad5tm1Huy/Smad5tm1.1Huy Tg(Tie1-cre)9Ref/0 (conditional) |
* | |||||||||||||||||||
| Smad5tm1Huy/Smad5tm1.1Huy Tg(Tek-cre)1Ywa/0 (conditional) |
* | |||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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